ORBITA CTO: The Sham-Controlled Trial That Shook CTO-PCI episode artwork

EPISODE · May 10, 2026 · 19 MIN

ORBITA CTO: The Sham-Controlled Trial That Shook CTO-PCI

from The IC Chat · host asper1971

In this episode host Ashish Pershad reviews the ORBITA CTO randomized, double-blind, sham-controlled trial that compared CTO-PCI to a placebo procedure, explaining the rigorous design, patient selection, masking methods, and statistical approach. Pershad summarizes the results showing significant symptom improvement with CTO-PCI, discusses clinical implications—blinding, careful case selection, and specialist referral—and outlines how this trial advances evidence for procedural interventions for patients with stable angina.

In this episode host Ashish Pershad reviews the ORBITA CTO randomized, double-blind, sham-controlled trial that compared CTO-PCI to a placebo procedure, explaining the rigorous design, patient selection, masking methods, and statistical approach. Pershad summarizes the results showing significant symptom improvement with CTO-PCI, discusses clinical implications—blinding, careful case selection, and specialist referral—and outlines how this trial advances evidence for procedural interventions for patients with stable angina.

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ORBITA CTO: The Sham-Controlled Trial That Shook CTO-PCI

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This episode was published on May 10, 2026.

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In this episode host Ashish Pershad reviews the ORBITA CTO randomized, double-blind, sham-controlled trial that compared CTO-PCI to a placebo procedure, explaining the rigorous design, patient selection, masking methods, and statistical...

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