Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research

Donghan “Mo” Yang, PhD, is a researcher in the field of data science and health informatics.  He joins us on OsteoBites to introduce the development of the Osteosarcoma Explorer (OSE), a data commons with clinical, genomic, protein, and tissue imaging data for osteosarcoma research. The OSE is one of the flagship projects cultivated within the CPRIT-funded Pediatric Cancer Data Core (Director: Yang Xie, PhD, Professor and Associate Dean of Data Science, UT Southwestern). The goal of the OSE project is to integrate publicly available and institutional osteosarcoma data of various types and share them with the research community via an interactive web interface. The OSE web portal is now accessible to the public at https://datacommons.swmed.edu/cce/ose.Dr. Yang is an Assistant Professor and a Texas Health Resources Clinical Scholar in the Quantitative Biomedical Research Center at Peter O’Donnell Jr. School of Public Health, UT Southwestern Medical Center. He also serves as the Director of Biostatistics and Data Science Core at UT Southwestern. Dr. Yang’s research focuses on developing methods, platforms, and infrastructure for the management, integration, and analysis of real-world healthcare data, including electronic health records, imaging, and molecular profiling data. He has led team efforts of building data commons – comprehensive database interfaced by user-friendly web portal – for adult and childhood cancers and other diseases. He also applies advanced analytics to gain insights from these real-world data resources.