Ovarian Longevity 101: How to Slow Aging and Stay Fertile After 30 with Dr. Melissa Cano

Your ovaries age faster than any other organ—but what if you could slow that process down? In this science-meets-soul conversation, I'm joined by Dr. Melissa Cano, cellular health expert and Director of Science at Spermidine Life (code: BIOHACKINGBRITTANY), to break down the latest research on spermidine—a natural molecule showing powerful potential in extending ovarian health, boosting fertility, and supporting graceful hormone transitions. We dive into the cutting-edge studies on how spermidine mimics estrogen therapy (without the risks), how it reversed mitochondrial aging in mouse eggs, and what this means for women in their 30s, 40s, and beyond. If you're thinking about preserving fertility, supporting perimenopause, or optimizing longevity as a woman—this episode is for you. WE TALK ABOUT: We Talk About: 05:25 – Spermidine research: From petri dishes to real-world results 10:10 – Why healthspan matters more than lifespan 18:10 – Why women feel aging faster than men 23:30 – The mouse study that "rejuvenated" old eggs 35:20 – Is it possible to test your ovarian mitochondrial health? 40:30 – Foundational fixes before the fancy biohacks 44:00 – Spermidine vs. NAD, rapamycin, and other trendy longevity pills 49:50 – New study: Spermidine vs. estrogen therapy—without the cancer risk 54:50 – Could 50 really be the new 30 for fertility? 1:02:20 – How to source (or eat) spermidine + Dr. Cano's parting advice SPONSORS: Swap restless nights for real recovery with Magnesium Breakthrough by BiOptimizers (code: BIOHACKINGBRITTANY) — the full-spectrum formula I trust for calmer nerves, balanced hormones, and deep, restorative sleep. RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. Spermidine LIFE website (code: BIOHACKINGBRITTANY) LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

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This episode was published on July 1, 2025.

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