Ozempic and Mounjaro Warning! What They’re Not Telling You! episode artwork

EPISODE · Aug 20, 2026 · 29 MIN

Ozempic and Mounjaro Warning! What They’re Not Telling You!

from Dr. Paika Podcast · host Mohammed Paika

#Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicineOzempic and Mounjaro can be powerful weight-loss tools — but they can also affect your body in ways many people aren't told before starting. In this video, I break down the real risks, the paradox in the trial data, and what to actually watch for.In this video I walk through why people with type 2 diabetes tend to lose less weight on these medications than people without it, why a meaningful share of the weight lost on GLP-1s can be muscle rather than fat, what the data actually shows about gastroparesis and other GI complications, what happens metabolically when you stop the medication, how bariatric surgery compares, and exactly what to do to protect your muscle and your health if you're on one of these drugs.Timestamps:00:00 The risks nobody tells you about01:12 Who I am, and why this topic keeps me up at night03:04 The paradox no one is talking about04:56 Why your brain needs data from your gut07:01 The detail your prescriber probably never mentioned09:26 The lesson every doctor should remember11:21 A quick word before we go further12:14 The muscle you didn't know you were losing17:03 When the stomach stops working20:16 What happens when you stop21:03 Why bariatric surgery tells a different story24:11 What to actually do about it26:30 The bottom line27:36 Where to go from here🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime AccessComprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost.https://www.drmohammedpaika.com📩 FREE GLP-1 Diet Cookbook + Weekly NewsletterGet weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity.https://www.drmohammedpaika.com/newsletter📚 The Weight Equation & The Physician’s PhysiquePhysician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living.https://www.drmohammedpaika.com/books👥 Metabolic Health CommunityLive Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support.https://www.skool.com/metabolic-health-community-5316👍 Like💬 Comment📌 Share🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutionsBohórquez DV, et al. Gut sensor cells & the vagus nerve. Science, 2018. https://doi.org/10.1126/science.aat5236Holst JJ. The physiology of glucagon-like peptide 1. Physiological Reviews, 2007. https://doi.org/10.1152/physrev.00034.2006Semaglutide weight loss with vs. without type 2 diabetes — meta-analysis. Pharmaceuticals (Basel), 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC12300051/ACCORD Study Group. Effects of intensive glucose lowering in type 2 diabetes. NEJM, 2008. https://www.nejm.org/doi/full/10.1056/NEJMoa0802743Gamble JM, et al. Insulin dosage and mortality — confounding example. Lancet Diabetes & Endocrinology, 2017. https://doi.org/10.1016/S2213-8587(16)30316-3Look M, et al. Body composition changes with tirzepatide (SURMOUNT-1). Diabetes, Obesity and Metabolism, 2025. https://doi.org/10.1111/dom.16275Wilding JPH, et al. Body composition analysis (STEP 1 study). Conference abstract. https://www.newswise.com/pdf_docs/16159288255831_Wilding%20Abstract.pdfWilding JPH, et al. Weight regain after stopping semaglutide (STEP 1 extension). Diabetes, Obesity and Metabolism, 2022. https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/Sodhi M, et al. GI adverse events with GLP-1 receptor agonists. JAMA, 2023. https://pubmed.ncbi.nlm.nih.gov/37796527/FDA. Wegovy (semaglutide) prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215256s007lbl.pdfObesity Surgery, 2023. https://pubmed.ncbi.nlm.nih.gov/36336720/Chris Christie's 2013 lap-band surgery. U.S. News & World Report. https://www.usnews.com/news/articles/2013/05/07/chris-christie-admits-to-lap-band-surgery⚕️ MEDICAL & EDUCATIONAL DISCLAIMERThis channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

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Ozempic and Mounjaro Warning! What They’re Not Telling You!

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