Papua New Guinean Challenges of TB in Pregnancy

Today we speak with Prof Mola, Dr Welch and Dr Visiliu about their amazing work tackling TB in pregnancy in Papua New Guinea. They talk about the epidemiological, geographical and social challenges of providing maternal TB care in PNG along with some insights into treatment and control.REFERENCES:Hamada, Yohhei, et al. "The safety of isoniazid tuberculosis preventive treatment in pregnant and postpartum women: systematic review and meta-analysis." European Respiratory Journal 55.3 (2020).Gupta, Amita, et al. "Timing of maternal isoniazid preventive therapy on tuberculosis infection among infants exposed to HIV in low-income and middle-income settings: a secondary analysis of the TB APPRISE trial." The Lancet Child & Adolescent Health 7.10 (2023): 708-717Lotia Farrukh, Ismat, et al. "Pregnancy and Birth Outcomes in Patients With Multidrug-Resistant Tuberculosis Treated With Regimens That Include New and Repurposed Drugs." Clinical Infectious Diseases (2023): ciad445.Arvidsson, Åsa, et al. "The cascade of care for pregnant women with latent tuberculosis infection in a high-income country." Infectious Diseases 55.9 (2023): 635-645.Gupta, Amita, et al. "Isoniazid preventive therapy in HIV-infected pregnant and postpartum women." New England Journal of Medicine 381.14 (2019): 1333-1346.Alene, Kefyalew Addis, Akilew Awoke Adane, and Alemken Jegnie. "Impact of multidrug-resistant tuberculosis and its medications on adverse maternal and perinatal outcomes: protocol for a systematic review and meta-analysis." BMJ open 9.12 (2019): e034821.