Part 1: GLP-1 Medications (Ozempic & Semaglutide): Nutrition, Weight Loss, and Muscle Health episode artwork

EPISODE · Feb 3, 2026 · 28 MIN

Part 1: GLP-1 Medications (Ozempic & Semaglutide): Nutrition, Weight Loss, and Muscle Health

from Wellness That Fits · host Cassie Groeschl, Dietitian

GLP-1 medications like Ozempic, Wegovy, Mounjaro, Zepbound, and semaglutide are everywhere—but what do they actually do in the body, who truly benefits from them, and where does nutrition fit in?In part one of this two-part series, Cassie breaks down the science behind GLP-1 receptor agonists using evidence, not hype. This episode explores:What GLP-1 medications and peptides are and how they work in the bodyMedical use vs. cosmetic or weight-loss-driven useHow GLP-1s impact appetite, insulin, gastric emptying, and calorie intakeRisks of muscle loss and potential bone density changesWhy protein intake, fiber, resistance training, and overall nutrition are criticalLifestyle habits that support natural GLP-1 productionWhat happens when people come off GLP-1 medications—and why weight regain and “food noise” aren’t willpower issues, but biologyCassie also explains why GLP-1s are metabolic tools, not magic fixes, and how working with a dietitian before, during, and after these medications can protect muscle mass, support gut health, stabilize blood sugar, and create sustainable habits that last beyond the prescription.If you’re considering GLP-1 medications, currently taking them, transitioning off, or wondering how to support your health naturally, this episode will help you make informed, compassionate, and science-based decisions—without fear, shame, or extremes.👉 Don’t miss Part 2, where we dive deeper into food noise, body image, and the psychology behind GLP-1 use.Chapters List:00:00 Introduction to GLP-1 Medications01:24 Understanding GLP-1 and Peptides04:15 Who is Using GLP-1 Medications?07:53 Mechanism of Action of GLP-1s10:18 Weight Loss and Health Considerations13:56 Nutritional Strategies for GLP-1 Users18:58 Transitioning Off GLP-1s and Dietitian Support23:23 Sustainable Health Beyond GLP-1sWellness That FIts📞 Book a FREE Discovery Call with Cassie: let's discuss your current health routine and what is standing in your way of the life and energy you desire.🧠 Join my Newsletter for weekly insider tips on brain optimization, meal prep, holistic nutrition, and wellness routines.🥬Follow me on Instagram:@wellnessthatfitsReferencesArticle in Lancet - lean muscle loss

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Part 1: GLP-1 Medications (Ozempic & Semaglutide): Nutrition, Weight Loss, and Muscle Health

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