PCOS Diagnosis and Metabolic Surveillance

This podcast episode delivers an exhaustive review of the diagnostic, phenotypic, and cardiometabolic framework of polycystic ovary syndrome, emphasizing strict adherence to the Rotterdam consensus criteria. Listeners will explore the specific phenotypic demarcations from classic high-risk metabolic subtypes to milder non-androgenic profiles, paired with a strategic four-step protocol to isolate the condition from clinical mimics like non-classic congenital adrenal hyperplasia and androgen-secreting tumors. The discussion details the post-receptor insulin signaling defects driving tissue-specific insulin resistance, the clinical superiority of the dynamic oral glucose tolerance test, and surveillance mandates for atherogenic dyslipidemia, metabolic syndrome, and steatotic liver disease.