PCSK9, visceral fat, and the modern metabolic environment

Because cholesterol is a fat-like substance, it cannot dissolve or travel freely in blood, which is mostly water. To move around, it must be packaged into microscopic transport particles called lipoproteins. One of these, LDL (low-density lipoprotein), acts as the main delivery vehicle, carrying cholesterol from the liver to cells that need it for repair or hormone production. In small amounts, LDL cholesterol is therefore completely normal and necessary. The problem only begins when too much LDL remains circulating in the blood for too long.For more details see the blog article https://www.scvc.co.uk/vat-trap/pcsk9-visceral-fat-and-the-modern-metabolic-environment/