Personalized metabolic modeling in Methylmalonic Aciduria

from JIMD Podcasts · host Journal of Inherited Metabolic Disease

A systems-level exploration of methylmalonic aciduria using personalized genome-scale metabolic models. Featuring Almut Heinken, Vito Zanotelli, and Jean-Louis Guéant, discussing fibroblast transcriptomics, TCA cycle anaplerosis, heme biosynthesis flux, and the promise of multi-omics-guided precision medicine. Personalized Genome-Scale Modeling Reveals Metabolic Perturbations in Fibroblasts of Methylmalonic Aciduria Patients Almut Heinken, et al https://doi.org/10.1002/jimd.70077

Episode metadata supplied by the publisher feed · Published Feb 17, 2026

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Personalized metabolic modeling in Methylmalonic Aciduria

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