Personalized metabolic modeling in Methylmalonic Aciduria...

What this episode covers

A systems-level exploration of methylmalonic aciduria using personalized genome-scale metabolic models. Featuring Almut Heinken, Vito Zanotelli, and Jean-Louis Guéant, discussing fibroblast transcriptomics, TCA cycle anaplerosis, heme biosynthesis flux, and the promise of multi-omics-guided precision medicine. Personalized Genome-Scale Modeling Reveals Metabolic Perturbations in Fibroblasts of Methylmalonic Aciduria Patients Almut Heinken, et al https://doi.org/10.1002/jimd.70077

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Frequently Asked Questions

How long is this episode of JIMD Podcasts?

This episode is 37 minutes long.

When was this JIMD Podcasts episode published?

This episode was published on February 17, 2026.

What is this episode about?

A systems-level exploration of methylmalonic aciduria using personalized genome-scale metabolic models. Featuring Almut Heinken, Vito Zanotelli, and Jean-Louis Guéant, discussing fibroblast transcriptomics, TCA cycle anaplerosis, heme biosynthesis...

Can I download this JIMD Podcasts episode?

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