Pharma 11: Nicotinic Signalling - Junctions, Gates, and Thresholds

from Clinical Deep Dives · host Dr Manaan Kar Ray

This is a free preview of a paid episode. To hear more, visit drmanaankarray.substack.comThis episode examines nicotinic receptor pharmacology at two critical crossroads: autonomic ganglia and the neuromuscular junction. Here, signalling is rapid, decisive, and threshold-dependent—very different from the modulatory tone of muscarinic systems. We explore how drugs that act at nicotinic receptors can stimulate, block, or exhaust transmission,…

Episode metadata supplied by the publisher feed · Published Jan 31, 2026

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Pharma 11: Nicotinic Signalling - Junctions, Gates, and Thresholds

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