Pharma 29: Heart Failure - Supporting the Failing Pump

This is a free preview of a paid episode. To hear more, visit drmanaankarray.substack.comThis episode reframes heart failure as a syndrome of maladaptive compensation. What begins as the body’s attempt to preserve perfusion—fluid retention, vasoconstriction, neurohormonal activation—gradually accelerates damage and inefficiency. We explore heart failure therapy as a coordinated effort to unload the heart, interrupt harmful signals, and rest…