Pharma 35: Immunosuppression - Choosing Restraint

This is a free preview of a paid episode. To hear more, visit drmanaankarray.substack.comThis episode examines immunosuppressants and tolerogens as instruments of intentional restraint. When immune activation becomes misdirected—against self, grafts, or chronic inflammation—therapy aims not to erase immunity, but to recalibrate it. We explore how different classes intervene at distinct checkpoints of immune activation, why timing and combin…