Pharma 57: β-Lactams - Breaking the Wall Without Breaking the System

from Clinical Deep Dives · host Dr Manaan Kar Ray

This is a free preview of a paid episode. To hear more, visit drmanaankarray.substack.comThis episode explores β-lactam antibiotics as the pharmacology of structural sabotage. By targeting cell wall synthesis-a feature humans do not possess-penicillins, cephalosporins, carbapenems, and related agents achieve extraordinary selective toxicity. We trace peptidoglycan assembly, penicillin-binding proteins, and bacterial autolysis to explain why…

Episode metadata supplied by the publisher feed · Published Feb 3, 2026

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Pharma 57: β-Lactams - Breaking the Wall Without Breaking the System

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