Pharmacogenomics: Why your DNA holds the key to better medication choices episode artwork

EPISODE · Apr 4, 2025 · 40 MIN

Pharmacogenomics: Why your DNA holds the key to better medication choices

from Genetics for Healthcare

This is GENETICS FOR HEALTHCARE—a podcast dedicated to helping patients and caregivers advocate for precision medicine in treatment, survivorship, disease screening, and prevention. #geneticsforhealthcareIn this podcast episode, Rome Madison and Kristine discuss pharmacogenomics (PGx), the study of how genetics influence individual responses to medications. Kristine explains that genetic variations influence liver enzymes in drug metabolism, causing differences in drug processing. PGx testing can prevent toxic buildup of prescription drugs, improve treatment outcomes, and save lives. For example, some people may process medications too slowly causing a buildup of the drug in the body that can lead to fatal toxicity. Some people metabolize drugs or too quickly, eliminating the drug from the body too fast, leading to reduced effectiveness. PGx testing, through a simple genetic panel, can identify these variations, helping healthcare providers tailor medications to individual patients. This approach can reduce adverse drug events, improve treatment outcomes, and lower healthcare costs. Kristine emphasizes the importance of patient advocacy and highlights studies showing significant reductions in hospitalizations and emergency visits with PGx guided care. The conversation underscores the potential of PGX to revolutionize precision medicine, improve patient safety and reduce healthcare costs. Genetics for Healthcare: Spotify: https://open.spotify.com/show/5tvMOrd9RyHLdOEGFNWavq?si=18815af6d1fe4da0 Facebook: https://www.facebook.com/GeneticsForHealthcare Instagram: https://www.instagram.com/geneticsforhealthcare/ TikTok: https://www.tiktok.com/@genetics.for.healthcare LinkedIn: https://www.linkedin.com/company/genetics-for-healthcare-podcast/ CPIC Guidelines: https://cpicpgx.org/guidelines/ #Pharmacogenetics #PersonalizedMedicine #HealthcareInnovation

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