EPISODE · Jan 26, 2026 · 41 MIN
Physio 08: Somatosensory Neurotransmission: Touch, Pain, & Temperature
from Clinical Deep Dives · host Dr Manaan Kar Ray
Touch, pain, and temperature feel immediate and personal, yet each sensation is the result of layered physiological translation. Mechanical force becomes electrical activity. Thermal change becomes coded frequency. Tissue threat becomes urgency.In this episode, Medlock Holmes investigates how the body senses and interprets the external world through the somatosensory system. We explore specialised receptors, labelled lines, receptive fields, and ascending sensory pathways, focusing on how different modalities are kept distinct—yet integrated—within the nervous system.Pain, in particular, is examined not as a single signal, but as a protective narrative shaped by intensity, timing, location, and modulation. This episode highlights why sensation is not a mirror of reality, but a carefully constructed message designed to guide behaviour.Here, physiology reveals a quiet truth:Sensation is not about accuracy.It is about usefulness.Key Takeaways* Sensory receptors transduce physical energy into neural signals* Different sensory modalities use distinct receptor types and pathways* Receptive fields and labelled lines preserve sensory specificity* Pain signalling balances protection with modulation* Central processing shapes perception as much as peripheral input This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit drmanaankarray.substack.com/subscribe
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Physio 08: Somatosensory Neurotransmission: Touch, Pain, & Temperature
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