EPISODE · Jul 16, 2026 · 12 MIN
Pirtobrutinib After Covalent BTK Inhibitor - Double Refractory CLL
from Oncology Times - OncTimes Talk
Patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) have poor outcomes after the failure of covalent Bruton's tyrosine kinase (BTK) inhibitor treatment, and new therapeutic options are needed. Pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor, was designed to re-establish BTK inhibition.
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