Placebos: Fake It 'Til Your Brain Makes It

Details Ever wonder why sugar pills can kill pain, or why reading a side effect list actually causes those symptoms? In this mind-bending episode, McKyler takes Daniel on a deep dive into the placebo and nocebo effects—where belief literally rewires your brain’s chemistry. From Benjamin Franklin debunking “animal magnetism” in 1784 to modern patients improving on pills they know are fake, we explore the wild history and cutting-edge neuroscience behind medicine’s most mysterious phenomena. Links​Open label placebo: can honestly prescribed placebos work?​Neurobiological Mechanisms of the Placebo Effect​Placebo effects on human μ-opioid activity during pain​Genetics and the Placebo Effect: the Placebome​Expectation and Dopamine Release: Mechanism of the Placebo Effect in Parkinson's Disease​Harnessing the power of placebos​The Story of the Placebo EffectPatronsThank you to all our patrons for your support!​Liz D.​Seth T.​Irvin H.​DaDog​Miles T.​Kirk K.DiscordJoin our Discord channel: ⁠https://discord.gg/FYg6T5q7xK⁠---