Polypharmacy 5 moments: Frailty: when less is more

In our final episode, we explore frailty, a state of reduced resilience that makes people—particularly older adults—more vulnerable to adverse drug effects and prescribing cascades. Those living with frailty often have multiple long-term conditions, take polypharmacy, and benefit from a more personalised, “less is more” approach. (12m59s) We discuss what frailty looks like in everyday community pharmacy encounters, which medicines to look out for, and how to identify potentially inappropriate medicines prescribed. Through practical examples, we show how to ask the right questions, focus on what matters most to patients, and collaborate with general practice to reduce overprescribing through Structured medication review referrals. We highlight why, in frailty, taking fewer medicines can reduce harm and improve outcomes. Lelly Oboh, Consultant Pharmacist (Care of Older People) and Older People Lead (NHS Specialist Pharmacy Service) Rakhi Aggarwal, Primary Care Lead (NHS Specialist Pharmacy Service)