Pomegranate: The most interesting thing about pomegranate is what your gut bacteria make from it episode artwork

EPISODE · Apr 30, 2026 · 4 MIN

Pomegranate: The most interesting thing about pomegranate is what your gut bacteria make from it

from NutraSift: The nutraceutical innovation podcast · host Siftlink SA

Pomegranate ellagitannins (punicalagins) are barely absorbed. Your gut microbiota converts them to urolithins, particularly urolithin A, which induces mitophagy (clearance of damaged mitochondria). This is one of the most validated mechanisms in longevity science. But only ~40% of people produce urolithin A efficiently. The fruit isn't the product; the metabolite is and most people can't make it.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/27400265/https://pubmed.ncbi.nlm.nih.gov/32694802/https://pubmed.ncbi.nlm.nih.gov/35118817/

Episode metadata supplied by the publisher feed · Published Apr 30, 2026

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