Positive ANA, No Diagnosis? A Rheumatologist Explains the 5 Real Causes — Including the COVID Connection Nobody Is Talking About episode artwork

EPISODE · May 18, 2026 · 14 MIN

Positive ANA, No Diagnosis? A Rheumatologist Explains the 5 Real Causes — Including the COVID Connection Nobody Is Talking About

from Thriving with Arthritis and Autoimmune Diseases -with Dr. Diana Girnita · host Dr. Diana Girnita MD, PhD

Got a positive ANA and no answers? Dr. Diana Girnita, double board-certified rheumatologist, explains exactly what it means, what causes it, and when to act.You just got a positive ANA test result. Your doctor referred you to a specialist. And now you are spiraling — searching online, terrified, completely alone with a number on a piece of paper that nobody properly explained to you.This episode is for you.Dr. Diana Girnita is a double board-certified rheumatologist, founder of Rheumatologist OnCall, and a physician who has guided thousands of patients through exactly this moment. In this episode she breaks down everything your doctor did not have time to explain — clearly, completely, and without the medical jargon.WHAT YOU WILL LEARN IN THIS EPISODEWhat the ANA test actually detects and why a positive result is a signal, not a sentence.What your titer number means — from 1 to 40 all the way to 1 to 320 — and the point at which it becomes clinically significant.The four ANA patterns — homogeneous, speckled, centromere, and nucleolar — and which autoimmune conditions each one points toward.The 5 real causes of a positive ANA: autoimmune diseases, chronic infections like EBV and Lyme disease, common medications including hydralazine and minocycline, certain cancers, and the cause that surprises almost every patient — being a completely healthy person.The exact red flag symptoms that mean you need to see a rheumatologist now, not in six months. Including morning stiffness lasting over an hour, a butterfly-shaped rash across the cheeks, Raynaud's phenomenon, dry eyes and dry mouth together, and symmetric joint swelling in both hands.The COVID-19 connection — why 30 to 60 percent of people who had COVID now test positive for ANA, when antibody levels peak and begin to decline, and when this becomes a genuine trigger for autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, lupus, and new-onset thyroid disease.The questions to bring to your next rheumatology appointment so you leave with real answers — not another referral.WHO THIS EPISODE IS FORThis episode is for anyone who has received a positive ANA result and has been dismissed, told to wait and see, or sent home without a clear explanation. It is for women navigating unexplained fatigue, joint pain, hair loss, and dry eyes who have been told their labs are normal. And it is for anyone who had COVID-19 and is now experiencing new symptoms they cannot explain.You are not imagining it. And you deserve a real answer.Timeline0:00 - 0:30: Introduction to the ANA test and common concerns.0:30 - 1:04: Overview of what a positive ANA test means.1:04 - 1:17: Explanation of the ANA test as a screening tool.1:17 - 1:55: Basics of antinuclear antibodies and how the test works.1:55 - 2:10: Understanding the test results: titer and pattern.2:10 - 2:24: Importance of titer levels and patterns.2:24 - 3:21: Detailed explanation of titer levels and their significance.3:21 - 4:16: Discussion on ANA patterns and their implications.4:16 - 4:41: Causes of a positive ANA result.4:41 - 5:38: Autoimmune diseases as a cause.5:38 - 6:04: Chronic infections as a cause.6:04 - 7:06: Medications that can cause a positive ANA.7:06 - 8:03: Cancer as a potential cause.8:03 - 9:10: Healthy individuals with a positive ANA.9:10 - 10:19: Symptoms that require immediate medical attention.10:19 - 11:41: Importance of early diagnosis and telehealth.11:41 - 12:37: COVID-19 and its impact on ANA results.12:37 - 14:28: Conclusion and call to action for comprehensive evaluation.Support the showMore info about Dr. Diana Girnita, MD PhDWebsite: https://rheumatologistoncall.com/Email: [email protected]: https://www.youtube.com/@rheumatologistoncallLinkedIn: https://www.linkedin.com/in/diana-girnita-md-phd-07b57810/Instagram: https://www.instagram.com/rheumatologistoncall/Facebook Page: https://www.facebook.com/RheumatologistOncall/Facebook Group: https://www.facebook.com/groups/3685130571554200 

Episode metadata supplied by the publisher feed · Published May 18, 2026

Embed this episode

Got a positive ANA and no answers? Dr. Diana Girnita, double board-certified rheumatologist, explains exactly what it means, what causes it, and when to act. You just got a positive ANA test result. Your doctor referred you to a specialist. And now you are spiraling — searching online, terrified, completely alone with a number on a piece of paper that nobody properly explained to you. This episode is for you. Dr. Diana Girnita is a double board-certified rheumatologist, founder of Rheumatol...

Distinct summary based on available episode metadata or transcript content.

NOW PLAYING

Positive ANA, No Diagnosis? A Rheumatologist Explains the 5 Real Causes — Including the COVID Connection Nobody Is Talking About

0:00 14:37

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

No similar episodes found.

No similar podcasts found.

Frequently Asked Questions

How long is this episode of Thriving with Arthritis and Autoimmune Diseases -with Dr. Diana Girnita?

This episode is 14 minutes long.

When was this Thriving with Arthritis and Autoimmune Diseases -with Dr. Diana Girnita episode published?

This episode was published on May 18, 2026.

Can I download this Thriving with Arthritis and Autoimmune Diseases -with Dr. Diana Girnita episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!