Precision Medicine Saves Dollars & Makes Sense: How Population Health Screening Can Save Lives for Less

Where did you grow up and what attracted you to a career in medicine?What is precision medicine?This phrase has been used primarily to describe a different approach to cancer care. tumor profiling – molecular characterization of a person’s cancer cells what drives itbut your POV is prevention, and implementing an pathway to integrate genetics and genomic information into the healthcare ecosystem to be acted upon at different points of care along a patient’s journeyWhen you started to build the program at The Christ Hospital in Cincinnati, how did you decide what you were going to go after? [HerCan testing + PGx]early detection -- St I-IIprevention – prophylactic surgeryavoid side-effects or drug interactions [adverse events]You must compete for resources. What motivated the hospital to want to invest in this kind of program which does not yield ROI immediately?Was there pushback?Who needs to champion this vision and work? What were the results?# patients testedpeople in high-risk programsmoney saved on unnecessary procedures or therapyBOD of MADP Alliance for Disease Prevention-Forgot to mention: MADP has rebranded from "Microbiome Alliance for Disease Prevention" to simply "MADP Alliance for Disease Prevention." Founders wanted to focus on Microbiome, but we've dramatically expanded scope :)CDC Chronic Disease fast factsAddressing Chronic DiseaseMedicare—93% & Medicaid—82% in 2022 – chronic disease spending People with chronic disease use a disproportionate share of health care resources90% prescription drugs = $4.5 trillion3-of-every 4 (75%) healthcare dollars spent on people with chronic conditionsDiabetes: ~$413 billion (2022) in medical costs and lost productivity.38M have diabetes + 98M pre-diabetesCKD $96 billionHeart Disease & Stroke $234 Billion/yr 🡺 $2 trillion by 2025kills more American than anything (1-in-4 deaths)HBP $79 billionEmployers loss of productivity – people w/top 10 chronic conditions absent/person ea yr = 164M work days lost = $184 billion in lost productivityDepression – 25.6 daysCancer 17 daysRespiratory – 15 Asthma – 12Migraines – 11Allergies – 8Heart Disease – 6Arthritis – 6Diabetes – 2HBP – 1