PREVIEW Aliquot #65: Concerns with chronic NSAID use

Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms, such as aspirin, ibuprofen, naproxen, and others. Most NSAIDs, with the exception of aspirin, work by inhibiting the activity of a family of enzymes called cyclooxygenases, which drive inflammatory processes. But because these inflammatory processes can be beneficial in some contexts and because the drugs often elicit off-target effects, there are some concerns about their use.  In this Aliquot, I describe current recommendations and concerns surrounding NSAID use.  (00:00) Introduction (02:58) Daily aspirin use and cardiovascular disease risk (clip from Q&A #9) (07:02) The pros and cons of low-dose aspirin (clip from Q&A #30) (11:43) Aspirin use and metastatic cancer risk (13:46) Aspirin vs other NSAIDs (15:20) Effects of ibuprofen on the kidneys, stomach, and muscles (clip from Q&A #14) (18:52) NSAIDs, heart attack, and stroke (20:04) Alternatives to NSAIDs Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more. Learn more and sign up at: https://www.foundmyfitness.com/aliquot