Privacy-First Research with OpenSAFELY • Eli Holderness & Hannes Lowette episode artwork

EPISODE · Jul 29, 2025 · 27 MIN

Privacy-First Research with OpenSAFELY • Eli Holderness & Hannes Lowette

from GOTO - The Brightest Minds in Tech · host Eli Holderness, Hannes Lowette & GOTO

This interview was recorded for GOTO Unscripted.https://gotopia.techRead the full transcription of this interview hereEli Holderness - Research Software Advocate at Bennett Institute for Applied Data Science, Speaker & Professional NerdHannes Lowette - Principal Consultant at Axxes, Monolith Advocate, Speaker & Whiskey LoverRESOURCESElihttps://bsky.app/profile/eli.holderness.devhttps://twitter.com/eliholdernesshttps://hachyderm.io/@elihttps://linkedin.com/in/eli-holderness-4890b886https://github.com/eli-miriamhttps://eli.holderness.devHanneshttps://bsky.app/profile/hanneslowette.nethttps://twitter.com/hannes_lowettehttps://github.com/Belenarhttps://linkedin.com/in/hanneslowetteLinkshttps://www.opensafely.orghttps://docs.opensafely.org/ehrqlhttps://github.com/opensafely-core/ehrqlDESCRIPTIONOpenSAFELY represents a revolutionary approach to medical research that prioritizes patient privacy while enabling valuable insights from healthcare data. Rather than giving researchers direct access to sensitive GP records, it allows them to submit code that runs in a secure environment, with only privacy-checked aggregated results returned.Hannes Lowette talks to Eli Holderness about how the system works, its benefits for ensuring reproducible science, the challenges of working with data not collected for research purposes, and its potential applications beyond healthcare. The approach balances the need for medical research with strict privacy protections, ensuring patients maintain trust in how their sensitive data is used.RECOMMENDED BOOKSBen Goldacre • Bad ScienceBen Goldacre • Bad PharmaAaron Parecki • OAuth 2.0 SimplifiedAaron Parecki • OAuth 2.0 ServersErdal Ozkaya • Cybersecurity: The Beginner's GuideSaleem Siddiqui • Learning Test-Driven DevelopmentJacqui Read • Communication PatternsBlueskyInstagramLinkedInFacebookCHANNEL MEMBERSHIP BONUSJoin this channel to get early access to videos & other perks:https://www.youtube.com/channel/UCs_tLP3AiwYKwdUHpltJPuA/joinLooking for a unique learning experience?Attend the next GOTO conference near you! Get your ticket: gotopia.techSUBSCRIBE TO OUR YOUTUBE CHANNEL - new videos posted daily!

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This interview was recorded for GOTO Unscripted. https://gotopia.tech Read the full transcription of this interview here Eli Holderness - Research Software Advocate at Bennett Institute for Applied Data Science, Speaker & Professional Nerd Hannes Lowette - Principal Consultant at Axxes, Monolith Advocate, Speaker & Whiskey Lover RESOURCES Eli https://bsky.app/profile/eli.holderness.dev https://twitter.com/eliholderness https://hachyderm.io/@eli https://linkedin.com/in/eli-holdernes...

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Privacy-First Research with OpenSAFELY • Eli Holderness & Hannes Lowette

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