Producing Beta Cells: Generation of Pancreatic islets from Stem Cells

Today on Diabetes Insights, Prof. Raphael Scharfmann (INSERM, France) and Dr. Valeria Sordi (San Raffaele Diabetes Research Institute, Italy) join our host, Vivienne Parry to discuss the progress and remaining challenges in creating functional, insulin-producing beta cells from stem cells. From the fundamental biology of pancreatic development to translational protocols for generating clinical-grade cells, our experts highlight how far the field has advanced and what hurdles remain before cell replacement therapies become a routine option for people with diabetes. They explore key questions around immune rejection, scalability, long-term viability of transplanted cells, and how the research community is navigating the complexities of cell manufacturing at clinical scale. Listen now for a fascinating look at how cutting-edge science is shaping the future of cell-based therapies in diabetes care.