Producing Stronger Vaccines Faster By Harnessing Bacteria

Vidcast:  https://www.instagram.com/p/DUmSfKQDoQz/Genetically modifying bacteria using AI-refined DNA leads to production of vaccines with 8-fold higher immunogenicity in a time-frame even 5 times shorter than even the speedy mRNA technology. Microbiologists at the University of Virginia and Duke University now report this proof-of-concept in the journal Vaccines.This novel approach utilizes inactivated bacteria programmed with synthetic DNA instructions to produce new, highly effective vaccine antigens in about 3 weeks. The DNA design is guided by AI protein-structure modeling. The resultant vaccines are stable at refrigerator temperatures. They are inexpensive to produce costing less than $1/dose. In contrast, mRNA vaccines require more complex manufacturing and ultra-cold storage. They require about 3 months or more to go from design to a test-ready product.Additional preclinical testing is needed before human trials, but the researchers predict that  this approach could transform how the world responds to future pandemics—by making vaccines faster, cheaper, and more accessible to everyone…..someday soon.https://www.news-medical.net/news/20260128/UVA-Health-scientists-pioneer-a-new-way-to-create-vaccines-far-more-quickly-than-ever-before.aspxhttps://www.mdpi.com/2076-393X/14/1/14#vaccines #bacteria #AI #mRNA