Professor Mihai Netea: How a vaccine can affect the innate immune system in profound ways we never thought possible

Mihai Netea, professor of experimental medicine at Radboud University, discovered that vaccines can affect the immune system in ways that alter the general defense against other infections. Here he tells the story about the surprising discovery of trained immunity, explains the mechanistic background (it can be explained very simply, using the bookmark as a metaphor), and we discuss the many potential implications and applications.