Prosion | Mission: unheilbare Krankheiten therapieren episode artwork

EPISODE · May 16, 2022 · 28 MIN

Prosion | Mission: unheilbare Krankheiten therapieren

from Innovation Pulse · host Frank Thelen

Ein radikal neuer Ansatz, der die Lebensqualität von Krebspatienten verbessern soll: Die von PROSION entwickelte und patentierte Baukasten-Technologie ermöglicht die Erstellung von Wirkstoffen für eine riesige Gruppe zuvor nicht erreichbarer Proteine im Körper, unter anderem solche, die im Zusammenhang mit Krankheiten wie Krebs, Alzheimer und Herz-Kreislauf-Erkrankungen stehen. Im Fokus steht aktuell die Entwicklung eines Krebsmedikamentes, mit dem Ziel, das Wachstum und speziell die Metastasierung von soliden Tumoren zu bekämpfen. Im Gegensatz zu aktuellen Krebstherapien hat dieser neue Ansatz zudem das Potenzial, Resistenzbildungen zu verhindern. Wir freuen uns sehr darüber, in diesen neuen, wichtigen Space einzusteigen und die Gründer Slim Chiha und Mutlu Yönel bei ihrer Mission - der Therapie unheilbarer Krankheiten - unterstützen zu können. Proceedings of the National Academy of Sciences of the United States of America, 2020. Designed Nanomolar Small-Molecule Inhibitors of Ena/VASP EVH1 Interaction Impair Invasion and Extravasation of Breast Cancer Cells; https://www.pnas.org/cgi/doi/10.1073/pnas.2007213117 European Journal of Organic Chemistry, 2018. Design and Synthesis of Building Blocks for PPII-Helix Secondary-Structure Mimetics: A Stereoselective Entry to 4-Substituted 5-Vinylprolines; https://doi.org/10.1002/ejoc.201701584

Ein radikal neuer Ansatz, der die Lebensqualität von Krebspatienten verbessern soll: Die von PROSION entwickelte und patentierte Baukasten-Technologie ermöglicht die Erstellung von Wirkstoffen für eine riesige Gruppe zuvor nicht erreichbarer Proteine im Körper, unter anderem solche, die im Zusammenhang mit Krankheiten wie Krebs, Alzheimer und Herz-Kreislauf-Erkrankungen stehen. Im Fokus steht aktuell die Entwicklung eines Krebsmedikamentes, mit dem Ziel, das Wachstum und speziell die Metastasierung von soliden Tumoren zu bekämpfen. Im Gegensatz zu aktuellen Krebstherapien hat dieser neue Ansatz zudem das Potenzial, Resistenzbildungen zu verhindern. Wir freuen uns sehr darüber, in diesen neuen, wichtigen Space einzusteigen und die Gründer Slim Chiha und Mutlu Yönel bei ihrer Mission - der Therapie unheilbarer Krankheiten - unterstützen zu können. Proceedings of the National Academy of Sciences of the United States of America, 2020. Designed Nanomolar Small-Molecule Inhibitors of Ena/VASP EVH1 Interaction Impair Invasion and Extravasation of Breast Cancer Cells; https://www.pnas.org/cgi/doi/10.1073/pnas.2007213117 European Journal of Organic Chemistry, 2018. Design and Synthesis of Building Blocks for PPII-Helix Secondary-Structure Mimetics: A Stereoselective Entry to 4-Substituted 5-Vinylprolines; https://doi.org/10.1002/ejoc.201701584

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Prosion | Mission: unheilbare Krankheiten therapieren

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This episode was published on May 16, 2022.

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Ein radikal neuer Ansatz, der die Lebensqualität von Krebspatienten verbessern soll: Die von PROSION entwickelte und patentierte Baukasten-Technologie ermöglicht die Erstellung von Wirkstoffen für eine riesige Gruppe zuvor nicht erreichbarer...

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