Prostate Cancer | Oncology Today: Recent Research Advances in Prostate Cancer and the Clinical Implications – A 2023 Post-ASCO GU Activity

Featuring perspectives from Drs Andrew J Armstrong and Rana R McKay, including the following topics: Introduction (0:00) Intensification of endocrine therapy: Emerging role in nonmetastatic disease; choice of androgen deprivation therapy (3:31) Management of castration-resistant M0 disease; PROTACs, CDK4/6 inhibitors and other new endocrine approaches (16:18) Hormone-sensitive metastatic disease — Choice of antiandrogen (26:48) Castration-resistant metastatic disease (37:06) Genomic evaluation; PARP inhibitors for metastatic disease (46:24) Ideal sequencing of PARP inhibitors; management of associated side effects (55:21) Biomarker testing; MSI-high disease; TKIs with immunotherapy; bispecific antibodies? (59:42) CME information and select publications