Psilocybin and Nausea

Nausea is a common side effect when ingesting psilocybin mushrooms, usually most pronounced during the “come up” and typically leveling out for the remainder of the trip, although the extent and duration of nausea can vary greatly among individuals.Today, we’ll look at a few different perspectives on why nausea can happen, as well as some tips for avoiding it. We’ll also share how nausea played an integral part in one client’s intentional psychedelic experience, so tune in for a comprehensive conversation surrounding nausea and psilocybin!Key TakeawaysDiverse Biological Triggers: Nausea is primarily caused by the interaction of fungal compounds (like indigestible chitin, tannins, and beta-glucans) with the human body, as well as the activation of 5-HT2A and 5-HT3 receptors in the gut.Physiological vs. Psychospiritual Lenses: Identifying the specific causes of discomfort is essential for choosing the right approach; symptoms may stem from physical digestion or from "somatic resistance" and emotional baggage.Strategic Remedies: Depending on the trigger, the transition can be managed through remedies like lemon tekking and dietary preparation, or by intentionally "leaning in" to the experience as a beneficial psychospiritual purge.-Psychedelic Passage is your partner in safe, supported, and effective psychedelic journeys. As the first concierge service in the U.S., we connect you with vetted facilitators who value integrity and expertise. We're glad you're here, and we look forward to supporting you on your journey.No mushroom source? No problem. Download our Free Psilocybin Sourcing Guide. Want guidance tailored to your need? Book a free Pathfinding Call for personal support. Curious or seeking connection? Join our online care community to learn, share, and grow with others. Join our next Q&A or Facilitator Chat for free.