Psilocybin, LSD & Marijuana: Ranking Drugs for Longevity (Part 2) episode artwork

EPISODE · Sep 11, 2025 · 56 MIN

Psilocybin, LSD & Marijuana: Ranking Drugs for Longevity (Part 2)

from Bryan Johnson Podcast · host Bryan Johnson

Should I try shrooms for science? In part two of three of our series investigating drugs for longevity, I’m putting psilocybin, LSD and DMT under the microscope - and revealing some pretty exciting research that connects psychedelics to longer lifespans. We’ll also talk about weed, and what the data says about marijuana for longevity.   Study Links: Psilocybin for Cancer Patients   LSD: Longevity in Worms Cannabis Use Disorder Increases Mortality Risk Marijuana Increases Epigenetic Aging Marijuana’s Impacts on Sleep  Improving Sleep with Medical Cannabis Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction  01:52 - First Experiences With Drugs  05:42 - Psychedelics in Society  13:29 - Psilocybin, LSD & DMT  34:35 - Marijuana  50:53 - Longevity Rankings

Should I try shrooms for science? In part two of three of our series investigating drugs for longevity, I’m putting psilocybin, LSD and DMT under the microscope - and revealing some pretty exciting research that connects psychedelics to longer lifespans. We’ll also talk about weed, and what the data says about marijuana for longevity.   Study Links: Psilocybin for Cancer Patients   LSD: Longevity in Worms Cannabis Use Disorder Increases Mortality Risk Marijuana Increases Epigenetic Aging Marijuana’s Impacts on Sleep  Improving Sleep with Medical Cannabis Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect:  X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram:  https://www.instagram.com/bryanjohnson   TikTok:  https://www.tiktok.com/@_bryan_johnson_ Chapters:  00:00 - Introduction  01:52 - First Experiences With Drugs  05:42 - Psychedelics in Society  13:29 - Psilocybin, LSD & DMT  34:35 - Marijuana  50:53 - Longevity Rankings

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Psilocybin, LSD & Marijuana: Ranking Drugs for Longevity (Part 2)

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Should I try shrooms for science? In part two of three of our series investigating drugs for longevity, I’m putting psilocybin, LSD and DMT under the microscope - and revealing some pretty exciting research that connects psychedelics to longer...

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