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EPISODE · Jun 21, 2026 · 1H 5M

PSYCH 037: Neuropsychiatric Aspects of Movement Disorders

from Clinical Deep Dives · host Dr Manaan Kar Ray

Movement disorders are often understood through their motor features - tremor, rigidity, slowness, or involuntary movements. Yet the same neural circuits that govern movement also influence emotion, motivation, and cognition. This chapter explores the neuropsychiatric dimensions of these conditions.In this episode, we examine how basal ganglia–thalamocortical circuits regulate not only motor output but also behavioural and emotional processes. Disorders such as Parkinson’s disease, Huntington’s disease, and other movement disorders reveal how disruptions in these circuits extend far beyond movement alone.We explore common neuropsychiatric features, including depression, apathy, anxiety, impulse control disorders, psychosis, and cognitive impairment. Some arise from the disease process itself; others emerge as consequences of treatment, particularly dopaminergic therapies.A key theme is overlap. The boundaries between motor, cognitive, and emotional systems are not fixed - they are deeply interconnected. Dysfunction in one domain often reverberates across others.This chapter challenges a narrow view of movement disorders. What appears as a disorder of movement is often equally a disorder of motivation, reward, and control.Key Takeaways* Movement disorders involve circuits that regulate both motor and non-motor functions.* Basal ganglia networks are central to action, motivation, and behaviour.* Neuropsychiatric features include depression, apathy, anxiety, and psychosis.* Dopaminergic treatments can influence behaviour and impulse control.* Cognitive impairment is common in several movement disorders.* Motor and psychiatric symptoms reflect shared underlying circuitry.* A comprehensive approach must address both motor and non-motor features. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit drmanaankarray.substack.com/subscribe

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