Psychedelics Promote Brain Plasticity by Binding to TrkB receptors episode artwork

EPISODE · Feb 18, 2024 · 4 MIN

Psychedelics Promote Brain Plasticity by Binding to TrkB receptors

from Higher Signal: Get Smarter. Faster. · host Higher Signal

Two years ago, I pondered the possibility of psilocybin binding directly to TrkB receptors - and it seems like the future is here. This recent study, "Psychedelics promote plasticity by directly binding to BDNF receptor TrkB", published in the renowned Nature Neuroscience journal, substantiates this hypothesis. In this video, I will explore the study's controversial findings regarding how psychedelics like psilocybin may enhance neuroplasticity - the brain's ability to form and reorganize synaptic connections. To stay up-to-date with the latest developments in this exciting field, don't forget to subscribe and hit the notification bell. Remember, sharing knowledge is the best way to expand it - so, share this video with your friends and colleagues interested in the field of psychedelics and neuropharmacology!IG: @neuropharmacistTwitter: @samuelkohtalawww.neuropharmacist.comFurther reading:Moliner, R., Girych, M., Brunello, C.A. et al. Psychedelics promote plasticity by directly binding to BDNF receptor TrkB. Nat Neurosci 26, 1032–1041 (2023). https://doi.org/10.1038/s41593-023-01316-5Maxemiliano V. Vargas et al. Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Science 379,700-706(2023). DOI: 10.1126/science.adf0435Nardou, R., Sawyer, E., Song, Y.J. et al. Psychedelics reopen the social reward learning critical period. Nature 618, 790–798 (2023). https://doi.org/10.1038/s41586-023-06204-3Referenced videos:https://youtu.be/vvZnqlyxjTYhttps://youtu.be/JHAyZoL7sYQ

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