PT403 – Melanie Pincus, Ph.D & Manesh Girn – Understanding the Brain: Psychedelic Neuroscience Demystified

In this episode, David interviews neuroscientist, artist, and educator, Melanie Pincus, Ph.D.; and Ph.D. candidate in Neuroscience, lead or co-author on over a dozen scientific publications, and regular contributor to PT, Manesh Girn.  They tell their stories of how they became interested in neuroscience, and stress the importance of staying radically open-minded (or "epistemically naive") when it comes to how much we can claim we understand about the brain, the mind-body connection, and consciousness itself – that while fMRI and other advances have brought us a long way, there are still a ton of "unknown unknowns," especially around creativity, decision making, and imagination. They discuss the misconception that we only use 10% of our brains; comparisons between the brain and the universe; society's misunderstanding of "happy hormones" (dopamine, serotonin, etc.); how chronic stress takes a toll on all parts of the body; how MDMA works with memory processing; and how stacking modalities with the psychedelic experience (like play or activities focused on emotion regulation) can really help with personal goals and growth.  They have taken their understanding and fascination with neuroscience and applied it to a new course in our Psychedelic Education Center: "Psychedelic Neuroscience Demystified: How Psychedelics Alter Consciousness and Produce Therapeutic Effects": an 8-week live course with 10 hours of prerecorded material and a built-in community. It was designed with practitioners and clinicians in mind, but with the goal of still being as accessible as possible for anyone who is curious about the neuroscience of psychedelics, and how that knowledge can help with preparation, the journey, integration, and working with a heightened window of neuroplasticity.  Class begins on May 17, and if you sign up before April 12, you can get $100 off! www.psychedelicstoday.com