EPISODE · May 1, 2026 · 5 MIN
Quercetin: The supplement that kills aging cells, literally!
from NutraSift: The nutraceutical innovation podcast · host Siftlink SA
Quercetin is a senolytic that selectively triggers apoptosis in senescent (zombie) cells by inhibiting BCL-2 family anti-apoptotic proteins. Dasatinib with quercetin is the gold-standard senolytic combination in clinical trials, shown to clear senescent cells and improve physical function in elderly subjects. This longevity mechanism makes quercetin the most underpriced ingredient in the supplement aisle. It sells as an "antioxidant" for $10/bottle but has a mechanism relevant to the $100B+ longevity market.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/31542391/https://pmc.ncbi.nlm.nih.gov/articles/PMC6796530/https://pmc.ncbi.nlm.nih.gov/articles/PMC8521777/
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Quercetin: The supplement that kills aging cells, literally!
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