Quick Hit | Why the Same Drug Can Cost $90 or $9 at the Same Pharmacy — A Doctor Explains episode artwork

EPISODE · Jun 12, 2026 · 11 MIN

Quick Hit | Why the Same Drug Can Cost $90 or $9 at the Same Pharmacy — A Doctor Explains

from Overheard In The Emergency Room · host Dr Adrian Cois MD

My pharmacy tried to charge me $90 for a generic nausea medication. Five minutes later, with a coupon I signed up for in the aisle, I paid $9. Same drug. Same store. Same five minutes.If that sounds impossible — or like a trick — this episode is for you.In Quick Hits Episode 5, I walk you through exactly how prescription drug pricing works in America, who is actually setting the price you pay (hint: not your insurance company, not the pharmacy), and the three-step habit you can use every single time you fill a script.This is one of those moments where a small amount of knowledge gives you real power.•  There is no single “real” price for your medication. Multiple negotiated prices exist, and which one you pay depends entirely on which contract you invoke at the counter.•  Pharmacy Benefit Managers (PBMs) — not your insurance company — do most of the actual price-setting. Three companies control 79% of all U.S. prescription drug claims.•  The “cash price” is almost never the real price. It’s a sticker price designed for patients who don’t know to ask for anything else • GoodRx isn’t cash. It’s a different PBM’s contract you can piggyback on.• Three habits, every prescription: Ask the cash price. Compare on GoodRx and Cost Plus Drugs. Choose the lowest legitimate option.•  The February 2026 PBM reforms are a real step forward — but none of it changes what you pay today.DisclaimerThis podcast is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment. Always consult your physician or pharmacist regarding your specific situation.

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Quick Hit | Why the Same Drug Can Cost $90 or $9 at the Same Pharmacy — A Doctor Explains

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