Rage, Brain Fog, and Midlife Neuroscience: Your Brain on Hormones Part 1 of 1 episode artwork

EPISODE · Jul 14, 2026 · 39 MIN

Rage, Brain Fog, and Midlife Neuroscience: Your Brain on Hormones Part 1 of 1

from The Luminescence Podcast with Schuyler Grant · host Luminescence

You're capable. You're high-functioning. And then something shifts. You can't remember words, you're snapping at everyone, you're lying awake at 3am soaked in sweat, or you're so flattened by anhedonia that nothing feels worth doing. In this episode of the Luminescence Podcast, Schuyler Grant sits down with Dr. Sarah de la Torre, Dr. Somi Javaid, and Elena Brower to get personal and then scientific about what perimenopause and menopause actually do to the brain. Dr. Somi opens with losing her speech mid-presentation on stage. Elena talks about white-hot rage that arrived at 47 with no warning. Dr. Sarah describes the moment she realized she could no longer tolerate the chaos she'd always managed with ease. They discuss: How estrogen, progesterone, and testosterone regulate dopamine, serotonin, GABA, and glutamate — and what happens when these hormones fluctuate wildly Why perimenopause can look like depression in one woman, anxiety in another, and new-onset ADHD in a third — and how clinicians tell the difference between hormonal changes and underlying psychiatric conditions How hot flashes and night sweats are actually a brain regulation problem, not just an ovary problem — and why sleep fragmentation is both symptom and accelerant The real cost of untreated menopausal symptoms — 900,000 women left the UK workforce, and $1.8 billion lost in the US economy How GLP-1 medications are unexpectedly quieting anxiety and rumination in midlife women — and why neuroinflammation might be the missing link For any woman wondering if she's losing her mind, or if there's a reason for the rage, the fog, and the 3am spiral. For information on our upcoming events, retreats, and to connect with specialists and other women in our online community, visit www.luminescence.health.  Presented by our sponsors: Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off the entire product line. Genova Connect: Save 20% on testing with code COMMUNE20 so you can stop guessing and make adjustments to support what matters. Visit connect.gdx.net. LivOn Labs: Get 15% off your first order of elite-absorption, foundational supplements that fit into your routine with code COMMUNE15 (valid through 6.30.26) at LivOnLabs.com. BiOptimizers: Go to bioptimizers.com/luminescence and use code LUMINESCENCE for 15% off. Try Schuyler's new personalized yoga app: https://schuylergrant.com/app

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