Ramie Darling , 10, hepatoblastoma , Boston, with Katie (mom), Raymond “Ramie” Sr., and Allison O'Neill, MD, pediatric oncologist, Jimmy Fund Clinic, Dana-Farber

Ramie Darling (RAY-ME), 10, hepatoblastoma (heh-puh-tow-bla-stow-muh), Boston, withKatie (mom), Raymond “Ramie” Sr., and Allison O'Neill, MD, pediatric oncologist, Jimmy FundClinic, Dana-Farber· Ramie is from Vero Beach, FL and came to Dana-Farber specifically to see Dr. AllisonO’Neill, who leads the pediatric liver tumor center in the Jimmy Fund Clinic. He was diagnosedin December 2022 with Stage IV Hepatoblastoma, a liver cancer. Ramie’s treatment has included8 months of chemotherapy, liver surgery, and he also had a full liver transplant. He is slated tobe done with active treatment after about 2 more months of chemotherapy.· He is a huge Boston sports fan and recently got the amazing opportunity to meetPatriots quarterback Mac Jones. He attended a training camp practice as well as a game, wherehe spent time with Mac and played catch on the field. It was an incredible experience. He saysthat he is a Boston sports fan because Florida gave him cancer, but Boston cured his cancer.Hepatoblastoma facts· Hepatoblastoma is a type of liver cancer that is usually found in babies and children up toage 3.· Hepatoblastoma is rare, diagnosed in fewer than one in a million children.· Children have a higher risk for developing hepatoblastoma if they have one of more ofthe following factors: were born prematurely with very low birth weights; have hemihyperplasia—one side of the body growing faster than the other; have an inherited conditioncalled familial adenomatous polyposis.· Affected family members develop multiple, initially noncancerous polyps in the colonthat become cancerous if not removed; have Beckwith-Wiedemann syndrome.· Babies with this disorder are large at birth; develop low blood sugar; and often havelarge tongues, large internal organs and problems in the area near their “belly buttons.”· The survival rate is more than 80% if the tumor is only in the liver and can be completelyremoved with surgery after chemotherapy. Allison O'Neill, MD· Dr. O’Neill is a clinician and scientist who spends 50% of her time treating patients withsolid tumors, with a special focus on treating patients with liver tumors, and 50% of her timeperforming clinical and preclinical research.· She is director of the Pediatric Liver Tumor Program therefore much of her researchfocuses on improving outcomes for patients with rare liver tumors.