Ranked Battle: Louisville vs Mississippi | Louisville Football News

College football’s biggest Week 1 showdown pits No. 24 Louisville against No. 9 Mississippi, with the Rebels favored at 72% to win by 6.5 points. Mississippi’s elite backfield, led by QB Trinidad Chambliss and RB Kewan Lacy, returns with a high-octane offense that averaged nearly 37 points per game last year. Louisville, meanwhile, is a wild card—returning just nine key players and sending first-time starter Lincoln Kienholz into battle against a top-5 pass defense. But don’t count out the Cardinals: their explosive running game, spearheaded by Isaac Brown’s 8.9 yards per carry, could keep pace with Mississippi’s leaky run defense, which surrendered over 150 yards per game. Expect fireworks—and the over on 55.5 total points is looking good. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/8be2195f0fd78da0