Renal: Testicular Cancer: Free MSRA Podcast

🎧 FREE MSRA PODCAST – Testicular Cancer: Rapid, High-Yield RevisionEssential facts on the most common cancer in young men – broken down for MSRA, UK practice, and clinical clarity.🧠 Key Learning PointsDefinition• Testicular cancer = Malignancy of the testicle (germ cell tumours most common)• Main types: Seminoma and Non-seminomatous germ cell tumours (NSGCTs)Epidemiology• 1% of all male cancers, but most common in ages 15–35• Peak incidence: UK men aged 15–49• Over 95% 5-year survival rate (highly curable if caught early)• Rising incidence in the UK; rare in boys under 10Risk Factors• Cryptorchidism (undescended testicle)• Family history (especially father/brother)• TGCT1 gene variant (up to 50× risk)• Other: HIV, infertility, infantile hernia, Kleinfelter syndrome, low birth weight, tall stature, testicular microlithiasisClinical Features• Painless lump or swelling in testicle (95% present this way)• Heaviness, dull ache, rarely pain• Gynaecomastia (breast swelling, β-hCG producing tumours)• Advanced: back pain (lymph node spread), cough/SOB (lung mets), leg swelling, supraclavicular nodeDiagnosis• Tumour markers: β-hCG, AFP, LDH• Scrotal ultrasound = key imaging• Staging CT chest/abdomen/pelvis• Definitive diagnosis: histology post-orchidectomyManagement• Surgery: Radical inguinal orchidectomy is first-line• Seminoma: surgery ± chemo (carboplatin), ± radiotherapy• NSGCT: surgery ± BEP chemotherapy (bleomycin, etoposide, cisplatin)• Fertility preservation: Offer sperm banking before treatment• Follow-up: Long-term, with tumour markers and imagingComplications• Infertility, hypogonadism, cardiovascular risk (from chemo/radiotherapy), neuropathy, hearing loss, secondary cancers• Relapse/metastasis• Psychological impact – essential to offer support• Most patients regain normal quality of life after treatmentPrognosis• Over 95% cure rate if found early• NSGCTs may have slightly less favourable prognosis than seminomas• Late relapse possible but uncommonMemory Aids:“Young, painless lump = think testicular cancer!”“Early diagnosis = high cure rate.”“Seminoma = sensitive to radiotherapy; NSGCT = BEP chemo.”📎 More Testicular Cancer Resources:📝 Revision Notes: https://www.passthemsra.com/topic/testicular-cancer-revision-notes-2/💬 Flashcards: https://www.passthemsra.com/topic/testicular-cancer-flashcards-2/🧠 Q&A Notes: https://www.passthemsra.com/topic/testicular-cancer-accordion-qa-notes-2/📝 Rapid Quiz: https://www.passthemsra.com/topic/testicular-cancer-rapid-quiz-2/📚 Renal Course: https://www.passthemsra.com/courses/renal-for-the-msra/🏷️ #MSRA #TesticularCancer #Renal #MSRARevision #PassTheMSRA #FreeMSRA #Urology #Oncology #MSRAFlashcards #MSRAQuiz #UKGuidelines #Survival #TesticularLump #CancerAwareness