Renovating Damaged Joint Cartilage

Vidcast:  https://www.instagram.com/p/DTduuSIDpnJ/Once joint cartilage is damaged or simply wears away it doesn’t heal. Patients are offered pain relief and, eventually if necessary, joint replacement.Stanford orthopedic surgery researchers now report in the journal Science a breakthrough that leads to cartilage regeneration. They find that blocking an protein called 15-PGDH, short for 15-hydroxy prostaglandin dehydrogenase, that increases with aging, permits cartilage regrowth in older mice and in those with knee injuries. The blocking drug also triggers cartilage regeneration in mice and in human knee cartilage samples obtained from patients undergoing knee replacement surgery.An oral version of this 15-PGDH blocking drug is now available for clinical trials.  Hopefully, this agent may reduce the need for joint replacements…..someday soon,https://scitechdaily.com/anti-aging-injection-regrows-knee-cartilage-and-prevents-arthritis/https://www.science.org/doi/10.1126/science.adx6649#cartilage #joints #pain #jointreplacement