Researching Oxidized High-Density Lipoprotein in Obese Adolescents

Host: Alan S. Brown, MD, FACC, FAHA, FNLA Obesity is associated with systemic inflammation and oxidative stress, the leading steps towards development of atherosclerosis. Myloperoxidase (MPO) mediated oxidative damage of high-density lipoprotein (HDL) leads to a dysfunctional HDL which likely becomes pro-atherogenic. But, what happens in our adolescent patients? Monica Marin, MD, pediatric endocrinology fellow at the University of Oklahome Health Sciences Center and winner of the NLA Young Investigator Award, investigated the cardiovascular risk factors that are present in childhood and the importance of understanding the impact of oxidized HDL. Download and listen today! Produced in Partnership with