Revelation 16

The bowls or vials pouring out the seven plagues. Are they physical real world problems and afflictions; or plagues of the mind/spirit/soul or a mix of both? They seem directed on the whole earth, particularly against those who don't know God. Can an unbeliever be convicted to go back to God within these plagues? (Could a believer become so jaded and cynical during this time that he stops believing and his heart becomes hardened to listening to the Holy Spirit?). The Battle of Armageddon.