EPISODE · Apr 16, 2026 · 36 MIN
Reverb Therapeutics Co-Founder & CEO David de Graaf and antibody expert Jonathan Davis discuss the science of bispecifics and multispecifics and what the future holds for these modalities
from The Studio at Kendall Square · host BiotechTV
They walk us through the history of bispecifics, which have been talked about since the early 2000's, and the use cases for them today. Plus, a deep dive into the science, which includes discussing your body's reaction to then, affinity & avidity, CMC, and 'bead-on-a-string' approaches that some have used lately. Finally, a discussion of what the future holds.
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Reverb Therapeutics Co-Founder & CEO David de Graaf and antibody expert Jonathan Davis discuss the science of bispecifics and multispecifics and what the future holds for these modalities
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