Rewarding Negative Findings: Fixing Research and the Future of Science I Patrick Malone

Welcome to episode Nr. 6 of "The DeSci Podcast"! In this episode, Patrick Malone, a physician-scientist turned investor at KDT Ventures where he invests in early-stage life science and healthcare, tells us about what drove his interest in investing in healthcare, what Tech-Bio is, and how it relates to the traditional understanding of Biotech.  He also explains, why machine learning is effective in drug discovery, the biggest problem facing scientific research and funding models today, the future of scientific research, and much more. Patrick Malone argued that rewarding negative findings which help to discover what doesn’t work or what isn’t true in a previous research publication will greatly reduce the problem of reproducibility.    Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.  ____   Timestamps:   0:00 Intro 0:44 Background story of Patrick Malone 1:25 What drove your earlier interests in Academia? 5:53 Why was Investing of major interest to you? 8:36 What is TechBio and how does it compare to the traditional understanding of Biotech? 13:19 How can TechBio deliver up to the expectations of people towards it? 18:13 Which other fields can the principles of TechBio be applied to? 21:54 Why is there a lesser ROI in TechBio and Biotech compared to other technologies? 25:24 What drives you to write? 27:34 How was your experience with working with both Academia and Ventures? 30:04 What is the biggest problem facing scientific research and funding models today? 32:25 How would not having to apply for grants change the research focus of scientists? 34:25 What is your take on making research open source? 37:27 How can these new developments come into actualization? 39:52 What happens when scientific discoveries are no longer understandable by humans? 43:28 What do you think more people should be paying attention to? 46:11 Ending and outro.   ____   If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at [email protected]   Special thanks to:    Alex LaBossiere (Host): https://twitter.com/adlabossiere (Check Alex his own podcast here: https://open.spotify.com/show/7lf0G6SBTArFlJYuHlPPoy?si=adcfa5f7a82d4708) Patrick Malone: https://twitter.com/patricksmalone ____   Let's connect:   Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao  Molecule - The future of medicine belongs to everyone