Rheumer Has It: Weight, GLP-1 and Arthritis episode artwork

EPISODE · Feb 19, 2026 · 37 MIN

Rheumer Has It: Weight, GLP-1 and Arthritis

from Arthritis Life · host Cheryl Crow

They also discuss safe, realistic strategies that support joint health, including tailored exercise and strength training, plus the emerging evidence on GLP-1 medications (like semaglutide/Ozempic/Wegovy) for people with obesity and arthritis. The key message: obesity is a treatable chronic condition, and care should be compassionate, individualized, and evidence-based.*Content note/ trigger warning: This episode includes discussion of body weight, obesity, BMI, and weight-loss medications (including GLP-1 drugs).  We approach this topic from a stigma-free, evidence-based perspective, as well as lived experience, but we know conversations about weight can be sensitive or activating, especially for those with a history of weight stigma, eating disorders, or body image challenges. Listener discretion encouraged.Episode at a glance:Weight and arthritis: inflammation + joint load (OA and inflammatory arthritis)Why adipose tissue can worsen pain and disease activityBMI limits: muscle loss, fat distribution, and rheumatoid cachexiaExercise myth-busting: movement helps when it’s tailored and gradualStrength training for knee support and better joint mechanicsGLP-1 medications (semaglutide, tirzepatide): what research shows so farStigma-free framing: obesity is chronic, not a personal failurePractical next steps and trusted resources (Arthritis Research Canada webinar)Medical disclaimer: All content found on Arthritis Life public channels (including Rheumer Has It) was created for generalized informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.Episode SponsorsRheum to THRIVE, an online course and support program Cheryl created to help people with rheumatic disease go from overwhelmed, confused and alone to confident, supported and connected. See all the details and join the program or waitlist now!  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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How does weight affect arthritis pain and inflammation, and what actually helps? In this episode* of Rheumer Has It, Cheryl Crow and Eileen Davidson talk with rheumatologist and obesity medicine specialist Dr. Derin Karacabeyli about the science of weight, adipose tissue, and arthritis. They explain how excess body fat can increase inflammation and joint stress, why BMI (Body Mass Index) isn’t a perfect measure, and how stigma and mental health impact weight management for people living with rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, and osteoarthritis.

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Rheumer Has It: Weight, GLP-1 and Arthritis

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