EPISODE · Apr 21, 2026 · 24 MIN
RHR: The GLP-1 Blind Spot: What Ozempic Won't Do for Your Metabolic Health
In this episode of Revolution Health Radio, Chris explores the science behind GLP-1 medications, including their powerful effects on appetite, weight loss, and cardiometabolic risk. He also uncovers the critical blind spots in the current conversation, including new research on long-term side effects, nutrient deficiencies, muscle loss, and the high rate of weight regain after discontinuation. You'll learn why these drugs may be effective in the short term but fall short of addressing the root causes of obesity and metabolic dysfunction. Chris also explains who may benefit most from GLP-1 therapy and how to use these medications as part of a comprehensive strategy that includes nutrition, resistance training, and lifestyle interventions. In this episode we discuss: How GLP-1 drugs work Proven benefits, common side effects, and discontinuation rates Emerging long-term risks of GLP-1 use The risk of nutrient deficiencies from reduced food intake Muscle loss & body composition changes Weight regain after discontinuing use The lack of root-cause treatments addressing diet, lifestyle, and metabolic drivers Who benefits most from GLP-1s vs. who may not Using GLP-1s as part of a broader health strategy Show notes: Links to all the studies mentioned in this podcast can be found here Nutrient Deficiency ebook by Chris Kresser Learn more about the Adapt Naturals Core Plus bundle, or take our quiz to see which products best suit your needs If you'd like to ask a question for Chris to answer in a future episode, submit it here Follow Chris on Instagram or Facebook Add back in what the modern world has crowded out and feel and perform your best with Adapt Naturals supplements. Learn more and place your order at AdaptNaturals.com. If you appreciate the show and want to help create a healthier and happier world, consider leaving a review!
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RHR: The GLP-1 Blind Spot: What Ozempic Won't Do for Your Metabolic Health
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