RHR: The Lipid Energy Model and Lean Mass Hyper Responders, with Dr. Nicholas Norwitz

In this episode of Revolution Health Radio, Chris Kresser sits down with Dr. Nicholas Norwitz to delve into the lipid energy model and the phenomenon of lean mass hyper-responders. Dr. Norwitz shares his perspective both as a researcher and as someone who personally experienced dramatic increases in LDL cholesterol levels after adopting a low-carb and ketogenic diet. They explore the recent shifts in our understanding of cholesterol's role in cardiovascular disease, particularly in individuals on low-carb diets who are lean but exhibit high LDL levels.  Dr. Norwitz also discusses his groundbreaking research, including a provocative self-experiment involving Oreos, that challenges conventional wisdom about cholesterol management. This episode promises to shed light on the complexities of heart disease risk, dietary impacts on lipid profiles, and the potential implications for future research and clinical practice. In this episode, we discuss: Lean Mass Hyper-Responders and Dr. Norwitz's Oreo vs Statin Study The Lipid Energy Model: A New Perspective Challenging Conventional Wisdom: LDL's Role in Cardiovascular Disease The Problematic Research Ecosystem for Nutrition and Metabolism Other Potential Risk Factors Contributing to Cardiovascular Disease Show notes: Research Paper: "Oreo Cookie Treatment Lowers LDL Cholesterol More Than High-Intensity Statin Therapy in a Lean Mass Hyper-Responder on a Ketogenic Diet: A Curious Crossover Experiment" Oreo vs Statin Tweet on Dr. Norowitz's X The Oreo vs Statin study YouTube video Dr. Norwitz on Twitter/X @nicknorwitz Professor William Cromwell on Twitter/X @lipoprotein Dave Feldman on Twitter/X @RealDaveFeldman Learn more about the Adapt Naturals Core Plus bundle or take our quiz to see which individual products best suit your needs Follow Chris on Twitter, Instagram, or Facebook If you'd like to ask a question for Chris to answer in a future episode, submit it here This episode of Revolution Health Radio is sponsored by LMNT. As a member of our community, LMNT has a very special offer for you. Get a free LMNT Recharge Sample Pack when you purchase any LMNT product at DrinkLMNT.com/Kresser. Add back in what the modern world has crowded out and feel and perform your best with Adapt Naturals supplements. Learn more and place your order at AdaptNaturals.com. If you appreciate the show and want to help create a healthier and happier world, consider leaving a review!