S1, E23 - CHiRP: AI-Enabled Early Detection of Psychosis Risk with Amar Mandavia, PhD & Enrique "Kike" Gutiérrez, PhD episode artwork

EPISODE · Feb 8, 2026 · 45 MIN

S1, E23 - CHiRP: AI-Enabled Early Detection of Psychosis Risk with Amar Mandavia, PhD & Enrique "Kike" Gutiérrez, PhD

from Practical AI in Healthcare · host Steven Labkoff, MD and Leon Rozenblit, JD, PhD

What if early signs of psychosis could be detected from how patients speak—not what they say, but how they organize their thoughts?Amar Mandavia (VA Boston, Boston University) and Enrique "Kike" Gutiérrez (Polytechnic University of Madrid) join hosts Steve Labkoff and Leon Rozenblit to discuss CHiRP, an AI tool that identifies formal thought disorder from routine clinical conversations. They explain why the gold-standard manual test takes 5+ hours, how their system reduces that to minutes, and the hard ethical questions around labeling patients as "at risk."Key topics: prodromal psychosis detection, NLP in mental health, clinical workflow integration, MIT linQ Catalyst, and the payer challenges that make prevention hard to fund.

What if early signs of psychosis could be detected from how patients speak—not what they say, but how they organize their thoughts?Amar Mandavia (VA Boston, Boston University) and Enrique "Kike" Gutiérrez (Polytechnic University of Madrid) join hosts Steve Labkoff and Leon Rozenblit to discuss CHiRP, an AI tool that identifies formal thought disorder from routine clinical conversations. They explain why the gold-standard manual test takes 5+ hours, how their system reduces that to minutes, and the hard ethical questions around labeling patients as "at risk."Key topics: prodromal psychosis detection, NLP in mental health, clinical workflow integration, MIT linQ Catalyst, and the payer challenges that make prevention hard to fund.

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S1, E23 - CHiRP: AI-Enabled Early Detection of Psychosis Risk with Amar Mandavia, PhD & Enrique "Kike" Gutiérrez, PhD

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What if early signs of psychosis could be detected from how patients speak—not what they say, but how they organize their thoughts?Amar Mandavia (VA Boston, Boston University) and Enrique "Kike" Gutiérrez (Polytechnic University of Madrid) join...

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