EPISODE · Jun 28, 2026 · 57 MIN
S1, E43 - Isaac "Zak" Kohane, MD, PhD (Chair, Biomedical Informatics, Harvard Medical School; founding Editor-in-Chief, NEJM AI)
from Practical AI in Healthcare · host Steven Labkoff, MD and Leon Rozenblit, JD, PhD
A quiet war is underway over who controls your health data in the age of AI, and the front-runners aren't the usual suspects. Dr. Isaac "Zak" Kohane, Chair of Biomedical Informatics at Harvard Medical School and founding editor of NEJM AI, traces the line from SMART on FHIR (the accidental standard he helped create in 2009) to today's battle for the doctor-facing AI layer, where companies like OpenEvidence are outrunning the EHR incumbents. He also unveils his Human Values Project, which measures the values embedded inside clinical AI models, and warns how easily payers and pharma could tune them. A two-act conversation about freeing data and guarding values.
What this episode covers
A quiet war is underway over who controls your health data in the age of AI, and the front-runners aren't the usual suspects. Dr. Isaac "Zak" Kohane, Chair of Biomedical Informatics at Harvard Medical School and founding editor of NEJM AI, traces the line from SMART on FHIR (the accidental standard he helped create in 2009) to today's battle for the doctor-facing AI layer, where companies like OpenEvidence are outrunning the EHR incumbents. He also unveils his Human Values Project, which measures the values embedded inside clinical AI models, and warns how easily payers and pharma could tune them. A two-act conversation about freeing data and guarding values.
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S1, E43 - Isaac "Zak" Kohane, MD, PhD (Chair, Biomedical Informatics, Harvard Medical School; founding Editor-in-Chief, NEJM AI)
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