S3E23: Understanding Brain Aneurysms in Women: Research Supported by The Bee Foundation

Women experience brain aneurysms at a higher rate than men. Are we alone in wondering what is behind this disparity? NO! This week, we welcome Rosalind Lai MD, a neurosurgeon performing research sponsored by a grant through The Bee Foundation. Dr. Lai and her team are trying to understand the role of the X chromosome in the development of cerebral aneurysms. Understanding this linkage could lead to the discovery of genetic markers for cerebral aneurysms and give insight into the gender differences we see in this condition. The hope would be that eventually we can test for genetic markers and provide treatments that turn down the expression of these genes which would lead to the prevention of brain aneurysms. Join Eryn, Alison, Rosalind and Erin Kreszl of The Bee Foundation (TBF) as we discuss TBF’s fourth pillar—research. Listen to learn more about brain aneurysms and this exciting research project!KeywordsThe Bee Foundation, brain aneurysm, research, gender differences, genetics, prevention, awareness, support, advocacyTakeaways·     The Bee Foundation supports research, advocacy, awareness, and support for brain aneurysm prevention.·     Brain aneurysms can be asymptomatic until they rupture, making awareness crucial.·     Women are at a higher risk for developing brain aneurysms compared to men.·     This research is focused on understanding the genetic and hormonal factors that contribute to aneurysm risk in women.·     The Bee Foundation has funded over $600,000 in research grants over the past 11 years.·     Genetic research aims to identify specific genes that may increase aneurysm risk.·     Understanding the role of the X chromosome could provide insights into gender differences in aneurysm development.·     Lifestyle factors like smoking and hypertension also play a significant role in aneurysm risk.·     The complexity of aneurysm development makes it a challenging area for research and prevention.·     Community support and engagement are vital for advancing research and awareness efforts.Sound Bites"We have four main program areas that we support.""What is an aneurysm?""We want to find these targets.""Aneurysm is a multi risk factor disease."Chapters00:00 Introduction to the Bee Foundation and Its Mission03:11 Understanding Brain Aneurysms06:10 Research Focus: Gender Differences in Aneurysms09:50 The Role of Genetics in Aneurysm Development19:30 Future Directions in Aneurysm Research26:38 Engagement and Support from the CommunityReach out toThe Bee Foundation https://www.thebeefoundation.org/ Email: [email protected], call 716-218-1000Eryn on IG @eryn_makingheadwaypodcastAlison on IG @alison_maknigheadwayodcastMHP on IG @makingheadwaypodcast Go to our website www.makingheadwaypodcast.com for full show notes and...